SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin B-6 [from 50 mg Coenzyme Pyridoxal-5-Phosphate (P-5-P) Monohydrate]
33 mg
1941%
Magnesium (from Magnesium Bisglycinate) (TRAACS®)
25 mg
6%

Top Medical Research Studies

4
Vitamin B6 and CFS relationship
Vitamin B status in patients with chronic fatigue syndrome.
Study highlights vitamin B6's role
We observed the functional status of vitamin B6, also known as pyridoxine, in patients suffering from chronic fatigue syndrome (CFS). Our study involved comparing 12 untreated CFS patients with 18 healthy individuals, matched for age and sex.

To assess the vitamin B6 status, we measured aspartate aminotransferase (AST) levels, among other key enzymes. Our findings revealed that the basal activity of AST was significantly lower in the CFS patients compared to the healthy controls.

This trend was consistent for other vitamins related to fatigue, like riboflavin and thiamine, where basal activity was also found to be lower in CFS patients. Importantly, even after supplementation in the lab, the overall activation ratios between both groups didn’t differ significantly.

Although our results suggest a reduced functional status of vitamin B6 in CFS patients, the lack of significant changes after vitamin activation indicates that vitamin B6 treatment alone may not be a definitive answer to combatting chronic fatigue syndrome. More research is necessary to understand the full role of B6 and its potential benefits.
Read More
8
Beta-glucan shows cognitive benefits
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Limited isolated effect of B6
We conducted a study exploring the effects of beta-glucan combined with vitamins, including vitamin B6, on individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). This research involved a 36-week trial where 65 participants were split into two groups: one received a daily supplement containing beta-glucan and vitamins, while the other received a placebo.

While the beta-glucan supplementation showed promising results in reducing cognitive fatigue, the specific impact of vitamin B6 on chronic fatigue syndrome was not clearly determined. This is because vitamin B6 was part of a combination treatment, making it difficult to assess its isolated benefits.

Ultimately, we observed that yeast-derived beta-glucan might hold potential in alleviating cognitive challenges associated with ME/CFS, which opens up avenues for further research. However, it’s important to remember that additional studies are needed to fully understand how vitamin B6 and other components contribute to this condition.
Read More

Most Useful Reviews

8.8
Improved overall tone
Vitamin B6 in the form of P-5-P has become essential in my daily diet. This product has significantly eased my fatigue and enhanced my overall tone. Since I began taking vitamin B6, I’ve noticed improvements in memory and concentration. The capsules are easy to swallow and gentle on the stomach. Being vegetarian-friendly, there are no concerns about animal products. I recommend it to anyone aiming to improve their health.
Read More
8.8
Fatigue alleviated
Excellent! My fatigue decreased whilst energy increased significantly after starting this supplement. The capsule form makes it easy to take.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
  • All Researches
8
Beta-glucan shows cognitive benefits
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Limited isolated effect of B6
We conducted a study exploring the effects of beta-glucan combined with vitamins, including vitamin B6, on individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). This research involved a 36-week trial where 65 participants were split into two groups: one received a daily supplement containing beta-glucan and vitamins, while the other received a placebo.

While the beta-glucan supplementation showed promising results in reducing cognitive fatigue, the specific impact of vitamin B6 on chronic fatigue syndrome was not clearly determined. This is because vitamin B6 was part of a combination treatment, making it difficult to assess its isolated benefits.

Ultimately, we observed that yeast-derived beta-glucan might hold potential in alleviating cognitive challenges associated with ME/CFS, which opens up avenues for further research. However, it’s important to remember that additional studies are needed to fully understand how vitamin B6 and other components contribute to this condition.
Read More
4
Vitamin B6 and CFS relationship
Vitamin B status in patients with chronic fatigue syndrome.
Study highlights vitamin B6's role
We observed the functional status of vitamin B6, also known as pyridoxine, in patients suffering from chronic fatigue syndrome (CFS). Our study involved comparing 12 untreated CFS patients with 18 healthy individuals, matched for age and sex.

To assess the vitamin B6 status, we measured aspartate aminotransferase (AST) levels, among other key enzymes. Our findings revealed that the basal activity of AST was significantly lower in the CFS patients compared to the healthy controls.

This trend was consistent for other vitamins related to fatigue, like riboflavin and thiamine, where basal activity was also found to be lower in CFS patients. Importantly, even after supplementation in the lab, the overall activation ratios between both groups didn’t differ significantly.

Although our results suggest a reduced functional status of vitamin B6 in CFS patients, the lack of significant changes after vitamin activation indicates that vitamin B6 treatment alone may not be a definitive answer to combatting chronic fatigue syndrome. More research is necessary to understand the full role of B6 and its potential benefits.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Improved overall tone
Vitamin B6 in the form of P-5-P has become essential in my daily diet. This product has significantly eased my fatigue and enhanced my overall tone. Since I began taking vitamin B6, I’ve noticed improvements in memory and concentration. The capsules are easy to swallow and gentle on the stomach. Being vegetarian-friendly, there are no concerns about animal products. I recommend it to anyone aiming to improve their health.
Read More
8.8
Fatigue alleviated
Excellent! My fatigue decreased whilst energy increased significantly after starting this supplement. The capsule form makes it easy to take.

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